Ilona Sunyovski

Ilona Sunyovski, a Ph.D. candidate at the National Heart and Lung Institute in London, has received IFER funding from 2019-2020 for her project, “Vascularized three-dimensional constructs for CRISPR/dCas9-monitored cardiac maturation in vitro.” The goal of Ilona’s project is to develop an approach to generate mature cardiac tissue from induced pluripotent stem cells. Using 3-D printing, she will generate a model that incorporates elements that better mimic the natural environment surrounding heart cells to facilitate their maturation. Such a model would greatly contribute to the reduction and replacement of animals currently used for cardiac research and therapeutic development.