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NIH Orders Immediate Shutdown of Intramural Human Embryonic Stem Cell Research
August 30, 2010
NIH's action—probably unprecedented in its history—is a response to a preliminary injunction on 23 August from U.S. District Judge Royce Lamberth. The judge ruled that the Obama policy allowing NIH funding to be used to study hESC lines violates a law prohibiting the use of federal funds to destroy embryos.
For more information see: Science
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Scientists Map All Mammalian Gene Interactions
August 9, 2010
The findings, published in the August issue of the journal Genome Research, will help researchers better understand which genes work together and shed light on how they collaborate to help cells thrive or die.
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Nanoscale DNA Sequencing Could Spur Revolution in Personal Health Care
August 21, 2010
That could open the door for more effective individualized medicine, for example providing blueprints of genetic predispositions for specific conditions and diseases such as cancer, diabetes or addiction.
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Genetics: Pet project
August 25, 2010
Stymied in the search for genes underlying human neuropsychiatric diseases, some researchers are looking to dogs instead.
For more information see: Nature
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New Parkinson's Gene Is Linked To Immune System
August 27, 2010
The long-term study involved a global consortium, including Johns Hopkins researchers from the Center for Inherited Disease Research who performed genome-wide association studies on more than 4,000 DNA samples — half from unrelated patients with Parkinson's and half from healthy "controls."
For more information see: EurekAlert!
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Reanimated ‘Junk’ DNA Is Found to Cause Disease
August 19, 2010
This is the first time, geneticists say, that they have seen a dead gene come back to life and cause a disease.
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Stem Cell Ruling to Be Appealed; Some Work to Stop
August 24, 2010
The government will quickly appeal a court ruling that undercut federally funded embryonic stem cell research, the Obama administration declared Tuesday, but dozens of experiments aimed at fighting spinal cord injuries, Parkinson's disease and other ailments probably will stop in the meantime.
For more information see: ABC News
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Better Way to Grow Stem Cells Developed
August 23, 2010
MIT chemical engineers, materials scientists and biologists have devised a synthetic surface that includes no foreign animal material and allows stem cells to stay alive and continue reproducing themselves for at least three months.
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Sharing of Data Leads to Progress on Alzheimer’s
August 12, 2010
In 2003, a group of scientists and executives from the National Institutes of Health, the Food and Drug Administration, the drug and medical-imaging industries, universities and nonprofit groups joined in a project that experts say had no precedent: a collaborative effort to find the biological markers that show the progression of Alzheimer’s disease in the human brain.
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NIH Launches Effort to Define Markers of Human Immune Responses to Infection and Vaccination
August 11, 2010
The investigators will take advantage of technological developments and advances in creating databases and developing mathematical models to identify and analyze the complex changes in immune profiles.
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Neurochip Technology Developed: Advances to Further Brain Research of Diseases Such as Alzheimer's and Parkinson's
August 10, 2010
The University of Calgary, Faculty of Medicine scientists who proved it is possible to cultivate a network of brain cells that reconnect on a silicon chip -- or the brain on a microchip -- have been involved in the development of new technology that monitors brain cell activity at a resolution never achieved before.
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Scientists Identify DNA That May Contribute to Each Person's Uniqueness
August 13, 2010
Building on a tool that they developed in yeast four years ago, researchers at the Johns Hopkins University School of Medicine scanned the human genome and discovered what they believe is the reason people have such a variety of physical traits and disease risks.
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Mouse Pain Study Stirs Debate
July 29, 2010
Canadian scientists vindicated after being accused of mistreating laboratory animals.
For more information see: Nature
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Drug Trials Funded by Industry Are More Likely to Publish Favorable Results, Researchers Find
August 2, 1010
When published results are systematically tracked for drug trials registered with ClinicalTrials.gov, those from industry-funded trials are the likeliest to be favorable to the drug in question.
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New Diagnostic Chip Able To Generate Single-Cell Molecular 'Fingerprints' For Brain Tumors
August 2, 2010
The ability to make these in vitro molecular measurements, or "fingerprints," marks a new advance in molecular diagnostics that could ultimately help physicians predict patient prognosis and guide personalized treatment.
For more information see: UCLA
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Pentagon Questions Drug Study on Troops
August 3, 2010
The Department of Defense is investigating whether 80 wounded American service members in Iraq were improperly used as subjects in a test of a possible treatment for brain injuries.
For more information see: Boston.com
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FDA Lifts Hold On Embryonic Stem Cell Trial
July 30, 2010
Regulators on Friday gave the all-clear to a clinical trial that will test embryonic stem cells as a treatment for spinal cord injury, potentially the first time embryonic stem cells are tested on humans.
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EPA Opens Access to New Toxicity Database
June 22, 2010
Public access to this information can potentially benefit ongoing toxicity research and reduce dependency on toxicity testing in animals.
For more information see: AltTox.org
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Predicting Drug Responsiveness in Cancer Patients
July 26, 2010
Specifically, the team found that human cancer cells with mutations in the PIK3CA gene responded to everolimus in vitro except when a KRAS gene mutation was also present.
For more information see: EurekAlert!
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Animal Connection: New Hypothesis for Human Evolution and Human Nature
July 20, 2010
Shipman proposes that the interdependency of ancestral humans with other animal species -- "the animal connection" -- played a crucial and beneficial role in human evolution over the last 2.6 million years.
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